By National Research Council, Institute of Medicine, Board on Health Sciences Policy, Division on Earth and Life Studies, Nuclear and Radiation Studies Board, Committee on State of the Science of Nuclear Medicine
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Extra info for Advancing Nuclear Medicine Through Innovation
FIGURE 3 Types of coincidences. Sidebar2-9, fig 3 Time-of-flight means that for each annihilation event the precise time that each of the coincident photons is detected is noted and the difference in arrival time is calculated. Since the closer photon will arrive at the detector first, calculating the difference in arrival time helps determine the location of the annihilation event between the two detectors. Theoretically, perfect time-of-flight information would eliminate the need to reconstruct images.
Today, the substantial nuclear physics research infrastructure that spawned many developments in nuclear medicine has diminished considerably. It has been offset to some extent by research infrastructure being developed to support efforts in biofuels12 research, homeland security, and 12 Biofuel is a renewable energy source that is composed of biological material. An example of a biofuel is ethanol. NUCLEAR MEDICINE 39 nanotechnology. However, the financial support needed to sustain research in nuclear physics and these new fields to advance nuclear medicine has been reduced, and the funding that remains is generally awarded to small teams of scientists for short durations.
11 Data taken from a given patient at different points in time or from different angles need to be transformed so comparisons can be made. Image registration is the process by which the different measurements are integrated. 9 Introduction to the Physics of PET A radiotracer that is labeled with a positron-emitting radionuclide, such as fluorine-18, is injected into the patient undergoing a PET scan. The radionuclides then decay, emitting positrons. The resulting positrons subsequently annihilate on contact with electrons within the body (Figure 1).