Judith E. Karp's Acute Myelogenous Leukemia (Contemporary Hematology) PDF

By Judith E. Karp

This is a well timed compilation of latest recommendations within the molecular pathogenesis and molecular treatment of acute myelogenous leukemia (AML). the point of interest is on chosen severe molecular determinants of AML pathogenesis and pathophysiology and the exploitation of those components via assorted healing brokers and modalities. there's an emphasis all through at the bidirectional circulation of data among the medical and laboratory arenas.

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Extra resources for Acute Myelogenous Leukemia (Contemporary Hematology)

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Diphtheria toxin-interleukin-3 fusion protein (DT(388)IL3;prolongs disease-free survival of leukemic immunocompromised mice. Leukemia 2003;17:155-159. Giles Fl, Kantarjian H, Cortes 1. Novel therapies for patients with chronic myeloid leukemia. Exp Rev Anticancer Ther 2004;4(2):271-282. Aguayo A, Kantarjian H, Manshouri T, et al. Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes. Blood 2000;96:2240-2245. Hussong JW, Rodgers GM, Shami PI. Evidence of increased angiogenesis in patients with acute myeloid leukemia.

Clin. Cancer Res 2004;10(10):3371-3376. Erratum in: Clin Cancer Res 2004;10(22):7787. 22 Part I I Ravandi and Giles 164. Sonneveld P. Multidrug resistance in hematological malignancies. J Intern Med 2000;247:521-534. 165. Ueda K, Cardarelli C, Gottesman MM, Pastan I. Expression of a full-length cDNA for the human "MDRl" gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc Natl Acad Sci USA 1987;84: 3004-3008. 166. Nooter K, Sonneveld P, Oostrum R, Herweijer H, Hagenbeek T, Valerio D.

Cancer Res 1999;59:2615-2622. 162. Cortes JE, Estey E, Giles FJ, et al. Phase I study of Bortezomib (PS-341, VELCADE), a proteasome inhibitor, in patients with refractory or relapsed acute leukemias and myelodysplastic syndromes. Blood 2002; 100:560. 163. Cortes J, Thomas D, Koller C, et al. Phase I study of bortezomib in refractory or relapsed acute leukemias. Clin. Cancer Res 2004;10(10):3371-3376. Erratum in: Clin Cancer Res 2004;10(22):7787. 22 Part I I Ravandi and Giles 164. Sonneveld P. Multidrug resistance in hematological malignancies.

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